lptG contributes to changes in membrane permeability and the emergence of multidrug hypersusceptibility in a cystic fibrosis isolate of Pseudomonas aeruginosa

ConclusionEvaluation of hypersusceptible mutants identified the association betweenlptG and a hypersusceptible phenotype. Modifications in lipopolysaccharide profiles suggests LptG modification interferes with lipopolysaccharide transport and contributes to hypersusceptibility.

Source: MicrobiologyOpen - April 11, 2019 Category: Microbiology Authors: Lucas B. Harrison, Randal C. Fowler, Baha Abdalhamid, Anna Selmecki, Nancy D. Hanson Tags: SPECIAL ISSUE: ANTIMICROBIAL RESISTANCE Source Type: research