Ketamine reverses neural changes underlying depression-related behaviors in mice

(NIH/National Institute of Mental Health) Researchers have identified ketamine-induced brain-related changes that are responsible for maintaining the remission of behaviors related to depression in mice. Ketamine treatment restored lost dendritic spines and rescued coordinated neural activity in the Prefrontal Cortex of the mice -- findings that may help researchers develop interventions that promote lasting remission of depression in humans. The study was funded by the National Institute of Mental Health (NIMH), part of the National Institutes of Health.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news