Risk factors for symptomatic venous thromboembolism during therapy for childhood acute lymphoblastic leukemia

Symptomatic venous thromboembolism (VTE) is an unpredictable and life-threatening toxicity, which occurs early in childhood acute lymphoblastic leukemia (ALL) therapy. Approximately 5% of children will experience VTE which is treated with anticoagulation. Asparaginase and corticosteroids are etiologic factors for VTE, however other clinical factors may modify this risk.

Source: Thrombosis Research - April 10, 2019 Category: Hematology Authors: M.K. Mateos, T.N. Trahair, C. Mayoh, P.M. Barbaro, R. Sutton, T. Revesz, D. Barbaric, J.E. Giles, F. Alvaro, F. Mechinaud, D. Catchpoole, R.S. Kotecha, L. Dalla-Pozza, M.C.J. Quinn, S. MacGregor, G. Chenevix-Trench, G.M. Marshall Tags: Full Length Article Source Type: research