Anti-TNF and postoperative complications in abdominal CD surgery.

CONCLUSIONS: Among patients treated with preoperative anti-TNF-α therapy, the risk of overall complications and infectious complications may slightly increase after abdominal surgery for CD. Nevertheless, the previous reports reviewed in this study are suffered from limitations. To rigorously evaluate the risk of anti-TNF-α therapy prior to surgery, large prospective studies with standardised criteria for assessing surgical complications and with proper adjustment for confounding variables are warranted.
PMID: 30947671 [PubMed - as supplied by publisher]

Source: Current Drug Targets - April 3, 2019 Category: Drugs & Pharmacology Authors: Yamamoto T, Teixeira FV, Saad-Hossne R, Kotze PG, Danese S Tags: Curr Drug Targets Source Type: research