Rapid progression in our understanding of extracellular vesicles and male infertility

Spermatogenesis is a complex process requiring the proper functioning of thousands of genes combined with the correct balance of hormones, temperature, and other environmental factors. Sperm isolated from the testicle, however, are generally immotile and immature —incapable of fertilizing an egg on their own, although they can be used for intracytoplasmic sperm injection. Sperm mature during transit through the epididymis, where morphologic, chemical, and other changes occur, giving them capacity for fertilization.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research