A phase I/II study of poziotinib combined with paclitaxel and trastuzumab in patients with HER2-positive advanced gastric cancer

ConclusionsThe MTD of poziotinib combined with paclitaxel and trastuzumab was 8  mg/day. This combination yielded promising anti-tumor efficacy with manageable toxicity in previously treated patients with HER2-positive GC.
Source: Gastric Cancer - Category: Gastroenterology Source Type: research