Are further studies needed to justify the use of proton therapy for paediatric cancers of the central nervous system? A review of current evidence

Although progress has been achieved in the treatment of CNS tumours, significant morbidity and mortality are still associated with childhood brain cancers. Current therapeutic strategies include a combination of surgery, chemotherapy and radiotherapy. While all treatment methods impose a certain risk, traditional photon-based treatments carry a high risk of adverse events, especially in very young patients. The more optimal physical and radiobiological properties of protons as compared to photons, have justified their implementation in radiotherapy, with several studies reporting promising results in otherwise difficult-to-treat cancers.
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Review Article Source Type: research