The effects of 7-week cognitive training in patients with vascular cognitive impairment, no dementia (the Cog-VACCINE study): A randomized controlled trial.

DISCUSSION: Computerized cognitive training significantly improved global cognitive function, which was supported by the improved brain plasticity. Incorporation of biomarkers should be implemented in cognitive training trials. PMID: 30894299 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research

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Conclusion
Source: blog.bioethics.net - Category: Medical Ethics Authors: Tags: Health Care syndicated Source Type: blogs
DiscussionComputerized cognitive training significantly improved global cognitive function, which was supported by the improved brain plasticity. Incorporation of biomarkers should be implemented in cognitive training trials.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Incurable and increasingly prevalent, Alzheimer ’s has long puzzled the research community. Now scientists believe the human body may be the best line of defenceHalf a million people in the UK areliving with Alzheimer ’s disease, the most common form of dementia. And while the risks generally increase with age, thousands are afflicted under the age of 65. Inheritable genetic conditions can lead to familial Alzheimer ’s, which can afflict people as young as 30.There is no known cure. Some medications can reduce memory loss and aid concentration, but these merely alleviate the symptoms or boost the performa...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Alzheimer's Medical research Health Immunology Society UK news Vaccines and immunisation Science Source Type: news
Sepsis and all-cause mortality rates higher in older people given no or delayed antibiotics Related items fromOnMedica Fund specialist dementia training to improve care and save money Antibiotics courses often longer than guidelines Adjuvanted trivalent flu vaccine best option for over-65s New evidence on benzodiazepine link to Alzheimer ’s Ibuprofen not a safe alternative to antibiotics for uncomplicated UTIs
Source: OnMedica Latest News - Category: UK Health Source Type: news
In this study, we show that calorie restriction is protective against age-related increases in senescence and microglia activation and pro-inflammatory cytokine expression in an animal model of aging. Further, these protective effects mitigated age-related decline in neuroblast and neuronal production, and enhanced olfactory memory performance, a behavioral index of neurogenesis in the SVZ. Our results support the concept that calorie restriction might be an effective anti-aging intervention in the context of healthy brain aging. Greater Modest Activity in Late Life Correlates with Lower Incidence of Dementia ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In conclusion, we found a gradient of increasing blood pressure with higher levels of BMI. The fact that this gradient is present even in the fully adjusted analyses suggests that BMI may cause a direct effect on blood pressure, independent of other clinical risk factors. PRRX1 as a Possible Point of Control for Remyelination https://www.fightaging.org/archives/2018/12/prrx1-as-a-possible-point-of-control-for-remyelination/ Researchers here outline what is possibly a new point of intervention in the processes that maintain the myelin sheath that wraps nerves. This sheath is vital to the correct operatio...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In this study, we found that TNF-α resulted in an impairment of autophagic flux in microglia. Concomitantly, an increase of M1 marker expression and reduction of M2 marker expression were observed in TNF-α challenged microglia. Upregulation of autophagy via serum deprivation or pharmacologic activators (rapamycin and resveratrol) promoted microglia polarization toward M2 phenotype, as evidenced by suppressed M1 and elevated M2 gene expression, while inhibition of autophagy with 3-MA or Atg5 siRNA consistently aggravated the M1 polarization induced by TNF-α. Moreover, Atg5 knockdown alone was suffic...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
This study is the culmination of a decade of research that has repeatedly demonstrated that this vaccine can effectively and safely target in animal models what we think may cause Alzheimer’s disease. I believe we’re getting close to testing this therapy in people.” ~ said Dr. Roger Rosenbe rg, founding Director of the Alzheimer’s Disease Center at UT Southwestern.What is the Difference Between Alzheimer ’s and DementiaThe study was conducted by the UT Southwestern ’s Peter O’Donnell Jr. Brain Institute.Subscribe to the Alzheimer's Reading RoomEmail:A DNA vaccine tested in mice red...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alzheimer's research alzheimers Beta Amyloid dementia dna health memory memory loss science tau vaccine Source Type: blogs
MONDAY, Nov. 26, 2018 -- An experimental Alzheimer's disease vaccine shows promise in animal tests, and researchers say it could have the potential to reduce dementia cases by half. In mice created to develop Alzheimer's, the vaccine triggered an...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
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