Cardiac myocyte-specific expression of beta3-adrenergic receptors sustains AMPK activation and glucose uptake while reducing hypertrophy following pressure overload

ConclusionWe conclude that cardiac myocyte-specific expression of B3AR concurrently prevents the development of insulin resistance and maintains AMPK activation contributing to the protection from hypertrophic remodeling under hemodynamic stress.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research