ERG11 gene polymorphisms and susceptibility to fluconazole in Candida isolates from diabetic and kidney transplant patients
CONCLUSIONS: Despite the high number of polymorphisms observed, the mutations occurred in regions that are not predicted to interfere with ergosterol synthesis, and therefore are not related to fluconazole resistance.
Conclusions: We found that perceived stigma in health care settings was a potential barrier to good health. Prior studies have illustrated that negative health outcomes are common for patients who avoid or delay care; thus, the unfortunate conclusion is that even in a diverse, heterogeneous community, stigma persists and may negatively affect well-being. Therefore, eliminating stigma in clinical settings should be a top priority for health care providers and public health professionals seeking to improve health equity.
[VOA] On the eve of World Diabetes Day, November 14, the World Health Organization is launching a new initiative it believes will allow greater access to life-saving insulin at lower prices for a greater number of people suffering from diabetes.
Is it time to re-evaluate the Oxford Classification for IgA nephropathy? This editorial explores the issues.Nephrology Dialysis Transplantation
(Duke-NUS Medical School) World's foremost society of kidney specialists highlights Singapore-led DYNAMO study that aims to improve understanding of diabetic kidney disease (DKD) complications and reduce DKD prevalence in Singapore by 30% over 5 years. Study is led by Duke-NUS Medical School Dean, Prof. Thomas Coffman.
(European Society of Cardiology) Women are most affected by the vascular complications of diabetes -- a situation likely to escalate in the coming decades, reports a paper published on World Diabetes Day in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology (ESC).
Publication date: Available online 12 November 2019Source: Brain, Behavior, and ImmunityAuthor(s): Célia Fourrier, Camille Kropp, Agnès Aubert, Julie Sauvant, Carole Vaysse, Jean-Michel Chardigny, Sophie Layé, Corinne Joffre, Nathalie CastanonAbstractMetabolic syndrome represents a major risk factor for severe comorbidities such as cardiovascular diseases or diabetes. It is also associated with an increased prevalence of emotional and cognitive alterations that in turn aggravate the disease and related outcomes. Identifying therapeutic strategies able to improve those alterations is therefore a major s...
TYPE 2 diabetes is a serious condition which affects a person ’s blood sugar levels, and left untreated, serious health conditions can occur. Medical expert, Dr Haris Ruther offers advice on spotting the symptoms and tips on how to deal with them.
CONCLUSIONS This was the first study to demonstrate an association between UNC13B gene polymorphisms and the susceptibility to DKD in a Chinese Han population with T2DM. The haplotype GGCCG was significantly associated with an increased risk of DKD. The findings highlight the joint effect of SNP markers in the pathogenesis of DKD. PMID: 31713534 [PubMed - in process]
This article is protected by copyright. All rights reserved.
In this study, we evaluated the genetic diversity among 120 isolates of Candida spp. obtained from diabetic patients, kidney transplant recipients and patients without any immune deficiencies from Paraná state, Brazil. The analysis was performed using the ITS1-5.8S-ITS2 region and a partial sequence of 28S rDNA. In the phylogenetic analysis, we observed a consistent separation of the species C. albicans, C. dubliniensis, C. glabrata, C. tropicalis, C. parapsilosis, C. metapsilosis and C. orthopsilosis, however with low intraspecific variability. In the analysis of the C. albicans species, two clades were formed. Cla...