TXNIP-mediated nuclear factor- κB signaling pathway and intracellular shifting of TXNIP in uric acid-induced NLRP3 inflammasome.

CONCLUSION: This study showed that activation of MSU-induced NLRP3 inflammasome requires TXNIP-mediated NF-κB signaling pathway and intracellular TXNIP shifting. PMID: 30833078 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30833078?dopt=Abstract

Source: Biochemical and Biophysical Research communications - February 28, 2019 Category: Biochemistry Authors: Kim SK, Choe JY, Park KY Tags: Biochem Biophys Res Commun Source Type: research