Longitudinal study on enterovirus A71 and coxsackievirus A16 genotype/subgenotype replacements in hand, foot and mouth disease patients in Thailand, 2000 –2017

Hand, foot and mouth disease (HFMD) is an acute febrile illness that mainly occurs in young children under 5 years of age, with characteristic vesicular eruptions on the hands, feet, mouth, and buccal cavity (Kashyap and Kashyap, 2015; Esposito and Principi, 2018). The disease can be caused by many enterovirus (EV) serotypes, but mainly by enterovirus A71 (EV-A71) and coxsackievirus (CV) A16 (CV-A16) (Ang et al., 2009; He et al., 2013; Huang et al., 2015a,b; Lei et al., 2015). Nevertheless, CV-A6 caused large epidemics in several Asia-Pacific countries from 2008 to 2017 and has subsequently become an endemic strain (Wu et al., 2010; Puenpa et al., 2013; Xu et al., 2015; Anh et al., 2018).

Source: International Journal of Infectious Diseases - January 9, 2019 Category: Infectious Diseases Authors: Pirom Noisumdaeng, Achareeya Korkusol, Jarunee Prasertsopon, Kantima Sangsiriwut, Kulkanya Chokephaibulkit, Anek Mungaomklang, Arunee Thitithanyanont, Rome Buathong, Ratigorn Guntapong, Pilaipan Puthavathana Source Type: research