CHCHD4 confers metabolic vulnerabilities to tumour cells through its control of the mitochondrial respiratory chain

ConclusionsOur study highlights an important role for CHCHD4 in regulating tumour cell metabolism and reveals that CHCHD4 confers metabolic vulnerabilities to tumour cells through its control of the mitochondrial respiratory chain and CI biology.

http://link.springer.com/10.1186/s40170-019-0194-y

Source: Cancer and Metabolism - March 5, 2019 Category: Cancer & Oncology Source Type: research