Repeated Finasteride Administration Induces Depression-Like Behavior in Adult Male Rats.

This study provides the evidence that an animal model of finasteride-induced depression is feasible to investigate the cellular and molecular mechanisms, and the pharmacology underlying the neuropsychiatric effects of finasteride. Further, these results provide insights into the potential involvement of neurosteroids in depression and will lead to the development of novel therapeutics for its treatment. PMID: 30836157 [PubMed - as supplied by publisher]
Source: Behavioural Brain Research - Category: Neurology Authors: Tags: Behav Brain Res Source Type: research