Lavender essential oil ameliorates depression-like behavior and increases neurogenesis and dendritic complexity in rats

Publication date: Available online 28 February 2019Source: Neuroscience LettersAuthor(s): Dalinda Isabel Sánchez-Vidaña, Kevin Kai-Ting Po, Timothy Kai-Hang Fung, Jason Ka-Wing Chow, Way Kwok-Wai Lau, Pui-Kin So, Benson Wui-Man Lau, Hector Wing-Hong TsangAbstractDepression is a major health issue that causes severe societal economic and health burden. Aromatherapy, a practice that uses essential oils for preventive and therapeutic purposes, represents a promising therapeutic alternative for the alleviation of depressive symptoms. Lavender essential oil (LEO) has been the focus of clinical studies due to its positive effect on mood. An animal model of chronic administration of high dose corticosterone to induce depression- and anxiety-like behavior and reduced neurogenesis was used to explore the biological changes brought by aromatherapy. Twenty-four adult male Sprague Dawley rats were randomly assigned into four groups: Control, corticosterone (Cort) group with high dose of corticosterone, LEO group with daily exposure to LEO by inhalation, and LEO + Cort. At the end of the 14-day treatment period, behavioral tests were carried out. Serum samples were collected 2-3 days after the 14-day period treatment and before perfusion to carry out biochemical analyses to measure BDNF, corticosterone and oxytocin. After perfusion, brains were collected for immunohistochemical analysis to detect BrdU and DCX positive cells in the hippocampus and subventricular...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research

Related Links:

Abstract Background: Chronic migraine with medication overuse headache (CM-MOH) is the most common type of chronic migraine, and it increases risk of stroke and white matter lesions. These pathologic changes could induce cognitive decline. However, the alteration of cognitive function in CM-MOH patients is not established. Therefore, we took this study to reveal the cognitive performances in CM-MOH. Methods: This cross-sectional study was conducted between December 2015 and January 2017. Patients were divided into CM-MOH, CMwoMOH (chronic migraine without medication overuse), and MO (migraine without aura) gr...
Source: Pain Research and Management - Category: Anesthesiology Authors: Tags: Pain Res Manag Source Type: research
This study aimed to investigate if the seleno-organic compound 1-methyl-3-(phenylselanyl)-1H-indole (MFSeI) reverses the depression- and anxiogenic-like behaviour, cognitive impairment and oxidative stress induced by the intra-cerebroventricular injection of streptozotocin (STZ; 0.2 mg/4 μl/per mouse) in Swiss male mice. Twenty-four hours after the STZ injection, mice were treated with MFSeI (10 mg/kg, intra-gastrically), or vehicle solution, once daily for seven days. The behavioural tests were performed 30 min after the final MFSeI administration, followed by euthanasia and collection of the cerebral cortex an...
Source: Pharmacology Biochemistry and Behavior - Category: Biochemistry Source Type: research
CONCLUSION: The PEI showed fair content validity, construct validity and internal consistency. However, the scale needs further development to improve measurement of change. PMID: 31198975 [PubMed - as supplied by publisher]
Source: Journal of Rehabilitation Medicine - Category: Rehabilitation Tags: J Rehabil Med Source Type: research
PURPOSE: We use data from a community sample, the Columbia County Longitudinal Study, which followed participants from childhood through adulthood, to examine the longitudinal relations between mental health (serious anxiety and serious depression) and off...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
ConclusionResults of the present study suggest that LDAEP can reflect adult ADHD symptoms in MDD. Auditory evoked potential appears to be a promising candidate as an evaluation tool for inattention and poor impulse control as well as emotional sensitivity.
Source: International Journal of Psychophysiology - Category: Psychiatry & Psychology Source Type: research
Conclusions: The prevalence of long-term posttraumatic stress disorder symptoms among family members of acute respiratory distress syndrome survivors is high. Family members with preexisting mental health disorders, recent experiences of serious physical illness, and family members of previously healthy patients are at increased risk for posttraumatic stress disorder symptoms.
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Clinical Investigations Source Type: research
ConclusionNo medical cause was found to explain the disability. Findings support that the condition is a form of IEI and belongs to functional somatic syndromes (FSS). Instead of endless avoidance, rehabilitation approaches of FSS are applicable.
Source: Safety and Health at Work - Category: Occupational Health Source Type: research
ConclusionThe most influencing spirituality dimensions are relationship with self and relationship with others. The sense of spirituality of female students is stronger than that of male students.
Source: Journal of Public Health - Category: Health Management Source Type: research
ConclusionMental states of surrender or preoccupation at the time of ingestion explain variance in mystical or adverse psilocybin experiences, and mystical experiences relate to long-term positive change. The capacity to recognize this optimal preparatory mental state may benefit therapeutic use of psilocybin in clinical settings.
Source: Psychopharmacology - Category: Psychiatry Source Type: research
Reasons It Is Hard to Get Help for My Addiction Breaking free from the prison that addiction holds you in is very difficult. It can often be a long, bumpy road to recovery because long-lasting sobriety takes a lot of effort. It can make many people stop to wonder: Why is it so hard to get help for my addiction? Roadblocks of Getting Help for My Addiction One of the many reasons you may be thinking, “why is it so hard to get help for my addiction?” is because there can be many roadblocks in the way. Some of these roadblocks include life obligations, the detox process, and the financial cost of treatment. Life Ob...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Addiction Recovery Addiction Stories Addiction Treatment and Program Resources Drug Treatment Substance Abuse addiction help admissions alcohol detox call for help drug detox medical detox medicated-assisted detox presc Source Type: blogs
More News: Anxiety | Aromatherapy | Brain | Depression | Lavender | Neurology | Neuroscience | Perfusion | Study