Comparison of Vascular Response to Statin Therapy in Patients With -vs- Without Diabetes Mellitus

Diabetes mellitus (DM) increases cardiovascular morbidity and mortality. A statin is routinely prescribed to patients with DM. However, whether a statin therapy is equally effective in plaque stabilization in DM patients compared to non-DM patients is unknown. A total of 117 lipid rich plaques were imaged in 90 patients (54 plaques in 41 DM patients and 63 plaques in 49 non-DM patients) with coronary artery disease who were treated with a statin and underwent serial optical coherence tomography imaging were included in this study (mean follow up period, 362 ± 38 days).

Source: The American Journal of Cardiology - February 22, 2019 Category: Cardiology Authors: Osamu Kurihara, Vikas Thondapu, Hyung Oh Kim, Michele Russo, Tomoyo Sugiyama, Erika Yamamoto, Francesco Fracassi, Yoshiyasu Minami, Zhao Wang, Hang Lee, Taishi Yonetsu, Ik-Kyung Jang Source Type: research