Novel Antiplatelet Therapies for Atherothrombotic Diseases.

Novel Antiplatelet Therapies for Atherothrombotic Diseases.
Arterioscler Thromb Vasc Biol. 2019 Feb 14;:ATVBAHA118310955
Authors: Majithia A, Bhatt DL
Abstract
Antiplatelet therapies are an essential tool to reduce the risk of developing clinically apparent atherothrombotic disease and are a mainstay in the therapy of patients who have established cardiovascular, cerebrovascular, and peripheral artery disease. Strategies to intensify antiplatelet regimens are limited by concomitant increases in clinically significant bleeding. The development of novel antiplatelet therapies targeting additional receptor and signaling pathways, with a focus on maintaining antiplatelet efficacy while preserving hemostasis, hold tremendous potential to improve outcomes among patients with atherothrombotic diseases.
PMID: 30760019 [PubMed - as supplied by publisher]

Source: Arteriosclerosis, Thrombosis and Vascular Biology - February 14, 2019 Category: Cardiology Authors: Majithia A, Bhatt DL Tags: Arterioscler Thromb Vasc Biol Source Type: research