GSE109827 Gut Microbiota from Human Autism Spectrum Disorder Induces Behavioral Deficits in Mice

Contributors : Sharon Gil ; Gandal MichaelSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe transplanted gut microbiota via fecal transfer from TD and ASD children into germ-free wild-type mice, and reveal that colonization with ASD microbiomes induces hallmark changes in sociability, vocalization, and stereotypies. The brains of mice receiving gut microbiota from ASD individuals display alternative splicing patterns for genes dysregulated in the human ASD brain.

http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE109827

Source: GEO: Gene Expression Omnibus - February 1, 2019 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research