Increased Donor Age Leads to Greater Severity of Ocular Graft-Versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation

Ocular graft-versus-host disease (GVHD) is a common complication of allogeneic hematopoietic stem cell transplantation (HSCT), affecting 40-60% of patients within 3 years after transplant. While the most common clinical manifestation is dry eye disease (DED), ocular GVHD can result in epithelial changes in the cornea that contribute to ocular pain and vision loss.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 349 Source Type: research