Human rabies post-exposure prophylaxis relative to the disease epidemiological status

This study evaluated the prophylactic measures adopted after attacks by dogs and cats in the main city of Northwester S ão Paulo State, based on the technical manual for post-exposure treatment, considering the not controlled (1990-1996) and controlled (1997-2010) rabies status. A retrospective analysis was done using the data from the SINAN records (W64-CID10) between 1990 and 2010. In most cases, the accidents wer e mild (76.9%), and biting animals were healthy (75.4%); therefore, no treatment was needed in 53.3% of the cases. In 64.6% of cases, the prescribed PEP treatment was inappropriate. The most indicated PEP treatments consisted of vaccine and RIG (43.4%), and either three doses of mouse brain vaccine or two doses of cell culture vaccine (76.5%), during the not controlled and controlled rabies periods, respectively. The treatment was more appropriate and followed the technical recommendations during controlled rabies periods compared to not controlled (p< 0.0001) periods. However, excessive application of RIG and rabies vaccine was observed in both periods.Resumo O objetivo da presente pesquisa foi avaliar a conduta profil ática adotada após agressões por cães e gatos no município de Araçatuba, SP, com base no Manual Técnico de Tratamento Antirrábico Humano e considerando-se as situações de raiva não controlada (1990-1996) e controlada (1997-2010). Foi realizada uma análise retrospectiva dos dados das fich as do SINAN (W64-CID10) preenchidas pelo serv...
Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research