Processing and coating of open-pored absorbable magnesium-based bone implants

Publication date: May 2019Source: Materials Science and Engineering: C, Volume 98Author(s): Stefan Julmi, Ann-Kathrin Krüger, Anja-Christina Waselau, Andrea Meyer-Lindenberg, Peter Wriggers, Christian Klose, Hans Jürgen MaierAbstractLarge bone defects or fractures must be treated with an implant or transplant. Resorbable implants are attractive as these require only one surgery, whereas bone autografts, which can be cut off from the same person's hip, require more than one procedure. Moreover, porous structures promote the ingrowth of the patient's bone. Thus, the objective of the present study was to develop open-pored biodegradable implant structures with different pore sizes that provide for both adequate degradation behaviour and mechanical properties that match with those of bone. The magnesium alloys LAE442 and La2 were employed in this study, as these materials are known to feature good biocompatibility and mechanical properties close to bone. It was possible to cast magnesium sponges with different pore sizes using the alloy LAE442. However, with the MgLa2 alloy, only sponges with a minimum pore size of 0.5 mm could be produced. Overall, the sponges cast with the LAE442 alloy showed higher strength, even though the strengths of the dense parts were similar in both alloys tested. In terms of castability and mechanical behaviour, the LAE442 alloy turned out to be more favourable. In order to adapt the implant degradation behaviour to the bone ingrowth behaviour, coa...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research