Stereotactic arrhythmia radioablation

Stereotactic arrhythmia radioablation Invasive catheter ablation is now an established modality of treatment for a wide variety of cardiac arrhythmias ranging from paroxysmal supraventricular tachycardias to life-threatening ventricular tachycardias. Now a new modality of stereotactic arrhythmia radioablation – a non invasive ablation using stereotactic body radiotherapy is being evaluated for drug refractory ventricular tachycardia which has failed catheter ablation [1]. ENCORE-VT trial (Electrophysiology-Guided Noninvasive Cardiac Radioablation for Ventricular Tachycardia) was a prospective single center study involving 19 patients. Seventeen of them had ischemic cardiomyopathy.  Most of the patients had prior catheter ablations. Those who had contraindications to catheter ablation were also considered. One of them had a mechanical aortic and mitral prosthetic valve. Another had a mobile left ventricular thrombus and the last had severe left ventricular dysfunction and medical comorbidities precluding hemodynamic support. Median follow up period was 13 months. Patients had either 3 or more episodes of sustained monomorphic VT or cardiomyopathy with more than 20% VPC load. They had failed at least one anti-arrhythmic drug therapy. Patients received a single dose of 25 Gy stereotactic radioablation to the arrhythmia target which was determined before the treatment schedule. Arrhythmia target was determined using a combination of cardiac CT, cardiac MRI, PET-CT, 12 lead...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: Cardiology Source Type: blogs