Incidence of Adenovirus Infection in Hematopoietic Stem Cell Transplantation Recipients: Findings from the AdVance Study

Adenovirus (AdV) is an increasingly recognized threat to successful outcomes after allogeneic hematopoietic stem cell transplantation (allo-HCT). Infection or reactivation is common after allo-HSCT, because of the immunosuppressive therapies required for successful transplantation [1 –4]. In most cases, emergent AdV infection is first identified within 100 days after transplantation [1–4]. Several small-scale studies have shown that systemic AdV infection increases the risk of death, particularly in cases of prolonged and unresolved infection [5–16].

Source: Biology of Blood and Marrow Transplantation - December 19, 2018 Category: Hematology Authors: Petr Sedl áček, Toni Petterson, Marie Robin, Ponni Sivaprakasam, Enrikas Vainorius, Tom Brundage, Aastha Chandak, Essy Mozaffari, Garrett Nichols, Sebastian Voigt Source Type: research