A rare brain tumor encountered: Phosphaturic mesenchymal tumor. Case report and review of the literature

Publication date: Available online 10 January 2019Source: Interdisciplinary NeurosurgeryAuthor(s): Uri P. Hadelsberg, Victoria Doviner, Meir Frankel, Lior Gonen, Gabriel Munter, Nevo MargalitAbstractRationalPhosphaturic mesenchymal tumors (PMTs) are rare tumors often causing tumor-induced osteomalacia (TIO), with surgical resection being the first line in the treatment of TIO. There are very few reports of PMTs located in the brain. The authors present one such case, it's management and outcome as well as a review of the literature.Patient concernsThe authors report of a 58 year old male with a background of osteoporosis, bone pain, muscle weakness and gait disturbances for the past several years. He presented to our institution with newly developed absence spells. He underwent imaging which revealed a brain tumor.InterventionsThe patient underwent surgery for what was suspected as a meningioma. A gross total resection was done. The pathological diagnosis was that of phosphaturic mesenchymal tumor.OutcomesRemoval of the tumor helped in alleviating the patient's back symptoms immediately after surgery. The patient was discharged home and was followed up by an endocrinologist, with improvement of his bone pain, his muscle weakness and his gait disturbances.LessonsPMT with involvement of the brain can be treated surgically. Removal of the tumor will alleviate symptoms in patients harboring this rare brain tumor.
Source: Interdisciplinary Neurosurgery - Category: Neurosurgery Source Type: research