Long term prognostic importance of late gadolinium enhancement in first-presentation non-ischaemic dilated cardiomyopathy

Presence of myocardial fibrosis in well-established non-ischaemic dilated cardiomyopathy (NIDCM) is associated with adverse clinical outcomes. However, the impact of myocardial fibrosis at first presentation in NIDCM, and its long-term association with left ventricular (LV) dysfunction, heart failure (HF) and ventricular arrhythmia (VA) remains unclear. We investigated whether the presence of myocardial fibrosis quantified by late gadolinium enhancement cardiovascular magnetic resonance (LGE-CMR) at presentation, is independently associated with long-term major adverse cardiovascular events (MACE) in patients with first presentation NIDCM.

Source: International Journal of Cardiology - January 9, 2019 Category: Cardiology Authors: Karthigesh Sree Raman, Gaetano Nucifora, Darryl P. Leong, Christian Marx, Ranjit Shah, Richard J. Woodman, Payman Molaee, Masoumeh Gh. Shirazi, Andrew D. McGavigan, Carmine G. De Pasquale, Joseph B. Selvanayagam Source Type: research