Ventricular Tachycardia (VT) Substrate Characteristics: Insights from Multimodality Structural and Functional Imaging of the VT Substrate Using Cardiac MRI Scar, 123I-Metaiodobenzylguanidine SPECT Innervation, and Bipolar Voltage

Conclusion: Structural and functional imaging demonstrated regional heterogeneities in the postischemic VT substrate not appreciated by any single modality alone. The coexistence of abnormal innervation and CMR scar may identify a particularly "proarrhythmic" adaptation and may represent a potential novel target for VT ablation.

Source: Journal of Nuclear Medicine - January 2, 2019 Category: Nuclear Medicine Authors: Imanli, H., Ume, K. L., Jeudy, J., Bob-Manuel, T., Smith, M. F., Chen, W., Abdulghani, M., Ghzally, Y., Mahat, J. B., Itah, R., Restrepo, A., See, V. Y., Shorofsky, S., Dilsizian, V., Dickfeld, T. Tags: Clinical Source Type: research