Identifying and Treating Opioid Side Effects The Development of Methylnaltrexone

Conclusions Our data demonstrate that intravenous methylnaltrexone can induce laxation and reverse slowing of oral cecal-transit time in subjects taking high opioid dosages. Low-dosage methylnaltrexone may have clinical utility in managing opioid-induced constipation.
Source: Anesthesiology - Category: Anesthesiology Source Type: research