Identifying and Treating Opioid Side Effects The Development of Methylnaltrexone
Conclusions Our data demonstrate that intravenous methylnaltrexone can induce laxation and reverse slowing of oral cecal-transit time in subjects taking high opioid dosages. Low-dosage methylnaltrexone may have clinical utility in managing opioid-induced constipation.
Source: Anesthesiology - Category: Anesthesiology Source Type: research
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