Validation of Urine-based Gene Classifiers for Detecting Bladder Cancer in a Chinese Study
Conclusions: Our study proves that our non-invasive diagnostic BC tests can be reproduced in independent cohorts and in an external laboratory. All the four gene classifiers have shown equal or superior performance to the current gold standard in the present and previously reported validation studies. Consequently, they may be taken for consideration as molecular tests applicable to clinical practice in the management of BC.Patient summary: Our gene classifiers achieve sensitivities up to 90% in HR NMIBC and MIBC patients, while this achievement is comparatively lower in LR NMIBC ones.
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Chengtao Han, Lourdes Mengual, Bin Kang, Juan Jos é Lozano, Xiaoqun Yang, Cuizhu Zhang, Antonio Alcaraz, Ji Liang, Dingwei Ye Tags: Research Paper Source Type: research
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