Treatment of psychiatric disturbances in common hyperkinetic movement disorders.

Treatment of psychiatric disturbances in common hyperkinetic movement disorders. Expert Rev Neurother. 2018 Dec 01;: Authors: Berardelli I, Pasquini M, Conte A, Bologna M, Berardelli A, Fabbrini G Abstract INTRODUCTION: This paper reviews studies that have assessed the treatment of psychiatric disturbances in dystonia, tic disorders, Tourette syndrome, Huntington's disease and essential tremor. Areas covered: We searched for papers in English in Pubmed using the following keywords: blepharospasm, cervical dystonia, arm dystonia, laryngeal dystonia, spasmodic dysphonia, tic disorders, Tourette syndrome, Huntington's chorea, essential tremor, depression, anxiety, obsessive compulsive disorders, attention deficit hyperactivity disorders, psychosis, apathy. Expert commentary: Although psychiatric disturbances are frequent in hyperkinetic movement disorders, few controlled studies have assessed the treatment of psychiatric disturbances in such disorders. In dystonia, none of the controlled studies conducted to date have demonstrated the efficacy of drug treatment for depression or anxiety. In TS, controlled studies have demonstrated the usefulness of drug treatment on obsessive compulsive disorders and attention deficit hyperactivity disorders. Behavioral interventions may also play a role. No controlled studies have been conducted on HD nor have any studies addressed the treatment of psychiatric disturbances in ET. We conclude that there is the need of controlled stud...
Source: Expert Review of Neurotherapeutics - Category: Neurology Tags: Expert Rev Neurother Source Type: research

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Authors: Dietrich DE, Bode L, Spannhuth CW, Hecker H, Ludwig H, Emrich HM Abstract BACKGROUND: Whether Borna disease virus (BDV-1) is a human pathogen remained controversial until recent encephalitis cases showed BDV-1 infection could even be deadly. This called to mind previous evidence for an infectious contribution of BDV-1 to mental disorders. Pilot open trials suggested that BDV-1 infected depressed patients benefitted from antiviral therapy with a licensed drug (amantadine) which also tested sensitive in vitro. Here, we designed a double-blind placebo-controlled randomized clinical trial (RCT) which cross-lin...
Source: BMC Pharmacology and Toxicology - Category: Drugs & Pharmacology Tags: BMC Pharmacol Toxicol Source Type: research
ConclusionThis study reports significant variability in sensory processing among children with DCD, ADHD and co-occurring symptoms using a population-based sample. These differences can contribute to understand how neurological and social factors correlates across diagnoses.
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
This correction reports and rectifies errors in several articles published in JAACAP between 2009 and 2011. Incorrect coding of the Suicidal Ideation Questionnaire-Jr resulted in the wrong reporting of the means for this measure and of the rate of participants with clinically significant suicidal ideation. The authors would like to apologize to the editorial staff and the readers for these mistakes.
Source: Journal of the American Academy of Child and Adolescent Psychiatry - Category: Psychiatry Tags: Correction Source Type: research
This study was aimed to estimate the prevalence of chronic pain in different regions of China. Data on pain and its treatment were collected from 9357 participants using questionnaires and telephone-based interviews, from 31 regions of China. Gathered data were then coded into electronic data acquisition system and descriptive and inferential statistical analysis was performed. Out of 9298 participants, the ratio of chronic pain was 31.54% with the proportion of male having chronic pain (33.86%) was higher than that of female (29.53%). The average age of participants with pain (45.02 ± 15.07 years) was higher than f...
Source: Libyan Journal of Medicine - Category: General Medicine Tags: Libyan J Med Source Type: research
CONCLUSION: Prison mental health teams face the challenge of identifying prisoners who need mental health services and providing early care to this vulnerable group; this challenge may offer a unique opportunity for intervention among a population that might not otherwise have had access to it. PMID: 32061382 [PubMed - as supplied by publisher]
Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research
PMID: 32068588 [PubMed - in process]
Source: Anesthesia and Analgesia - Category: Anesthesiology Authors: Tags: Anesth Analg Source Type: research
Publication date: Available online 19 February 2020Source: Pharmacology Biochemistry and BehaviorAuthor(s): Aaron Ettenberg, Kathy Ayala, Jacob T. Krug, Lisette Collins, Matthew S. Mayes, Matthew P.A. FisherAbstractSub-anesthetic doses of ketamine produce an increase in rodent ambulation that is attenuated by co-administration of naturally-occurring lithium (LiN), the drug most commonly employed in the treatment of bipolar illness. As a consequence, ketamine-induced hyperactivity has been proposed as an animal model of manic behavior. The current study employed a modified version of this model to compare the potency of LiN...
Source: Pharmacology Biochemistry and Behavior - Category: Biochemistry Source Type: research
Publication date: Available online 19 February 2020Source: Chemico-Biological InteractionsAuthor(s): Guo-liang Liu, Yun-feng Cui, Chang Lu, Peng ZhaoAbstractKetamine is gaining ground as a potential treating depression because it has a distinct mode of action than typical drugs that influence monoamine neurotransmitters including noradrenaline, dopamine, or serotonin. Ketamine is thought to act by blocking N-methyl-d-aspartate (NMDA) receptors in the brain, which interact with the amino acid neurotransmitter glutamate. The resultant chemical changes in the brain caused by ketamine are not yet fully understood but could inv...
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
This study suggests that forgiveness may serve as a protective factor and provide an effective means for reducing the negative association between workplace bullying and negative outcomes. PMID: 32063074 [PubMed - as supplied by publisher]
Source: Stress - Category: Research Tags: Stress Source Type: research
Authors: Hakim SM, Elfawy DM, Elserwi HB, Saad MK Abstract INTRODUCTION: The aim of this review is to examine current evidence on value of new ST-segment or T-wave changes for prediction of major adverse cardiac events (MACE) after vascular surgery. EVIDENCE ACQUISITION: We searched PudMed, EMBASE and Cochrane Library databases for studies examining the relation between new ST-segment elevation or depression or T-wave inversion and MACE following vascular surgery. MACE was defined as fatal or non-fatal myocardial infarction, cardiac death, unstable angina, cardiac arrest, congestive heart failure, ischemic pulm...
Source: Minerva Anestesiologica - Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research
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