sST2 as a Novel Biomarker for the Prediction of In-hospital Mortality after Coronary Artery Bypass Grafting.

CONCLUSION: sST2 values are associated with in-hospital mortality after CABG surgery and postoperative and pre-to-post operative sST2 values improve prediction. Our findings suggest that sST2 can be used as a biomarker to identify adult patients at greatest risk of in-hospital death after CABG surgery. Data availability statement: The data that support the findings of this study are available from the Northern New England Cardiovascular Disease Study Group Biomarker Study. Restrictions apply to the availability of these data, which were used under licence for this study. Data are available with permission from of the Northern New England Cardiovascular Disease Study Group and IRB approval. CLINICAL SIGNIFICANCE: Preoperative, postoperative, and pre-to-postoperative sST2 values can be used as a biomarker to identify adult patients at greatest risk of in-hospital morality after CABG surgery. CLINICAL SIGNIFICANCE: Preoperative, postoperative, and pre-to-postoperative soluble suppression of tumorgenicity 2 (sST2) values can be used as a biomarker to identify adults at greatest risk of in-hospital morality after CABG surgery. Postoperative and per-to-postoperative sST2 in combination with other established clinical risk factors for in-hospital mortality after CABG surgery can improve the ability of the surgical care team to more accurately identify the risks of CABG surgery. This improvement in prediction of early mortality can assist surgical care teams to determ...
Source: Biomarkers - Category: Research Tags: Biomarkers Source Type: research