Predictors of polymyxin B treatment failure in Gram-negative healthcare-associated infections among critically ill patients

ConclusionsTo the best of our knowledge, this is the first report on the association of inadequate dose of polymyxin B (<15,000 units/kg/day) with poor outcome in critically ill patients. Besides that, further clinical studies are warranted to evaluate the use of cefoperazone/sulbactam as second antibiotic in the combination therapy.
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research