The cardiac electrophysiology effects of higenamine in guinea pig heart

ConclusionWe show for the first time that HG produced a predominant action on the sinoatrial node. HG appears to control the cardiac electrophysiology through its predominant effect on the sinoarial node cells, without induction of the ectopic activity that causes cardiac arrhythmias. Thus, HG might be useful for the treatment of bradycardia.
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research