In Situ Hybridization of HBZ and Tax in FFPE Samples from ATLL Patients and Its Association with Clinicopathological Characteristics

ConclusionThe RNA scope assay is useful for detecting low expressing mRNA in FFPE tissue samples. Our data suggest that ISH of HBZ and Tax can detect differences in clinicopathological characteristics of ATLL patients. In clinical and cell samples, HBZ and Tax might be involved in the pathogenesis of ATLL.DisclosuresNo relevant conflicts of interest to declare.DisclosuresAsano: Takeda: Honoraria; Chugai Pharma: Honoraria; Celgene: Honoraria.

Source: Blood - November 21, 2018 Category: Hematology Authors: Yamada, K., Miyoshi, H., Takeuchi, M., Asano, N., Shimono, J., Arakawa, F., Nakashima, K., Sato, K., Seto, M., Ohshima, K. Tags: 624. Hodgkin Lymphoma and T/NK Cell Lymphoma-Clinical Studies: Poster I Source Type: research