Novel Antibodies Against Glycoprotein Ib{alpha} Inhibit Pulmonary Metastasis By Affecting Vwf-Gpib{alpha} Interaction

Conclusion:Our results therefore supported the hypothesis that GPIbα contributes to tumor metastasis, and suggested potential value of using anti-GPIbα mAb to suppress cancer metastasis.DisclosuresLi: Neoletix: Consultancy, Equity Ownership.

Source: Blood - November 21, 2018 Category: Hematology Authors: Yingxue, Q., Chen, W., Xu, K., Wu, F., Fan, X., Ren, S., Liu, J., Deng, W., Zhang, J., Li, R., Liu, J., Liang, X. Tags: 301. Vascular Wall Biology, Endothelial Progenitor Cells, and Platelet Adhesion, Activation, and Biochemistry: Poster I Source Type: research