Comparison of non ‐invasive tests with invasive tests in the diagnosis of celiac disease

ConclusionWhen serological tests, HLA typing, and clinical symptoms are all in favor of CD, biopsy may not be performed in selected adult CD patients.
Source: Journal of Clinical Laboratory Analysis - Category: Laboratory Medicine Authors: Tags: RESEARCH ARTICLE Source Type: research

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Erratum to "Association of Tissue Transglutaminase Antibody Titer with Duodenal Histological Changes in Children with Celiac Disease". Gastroenterol Res Pract. 2019;2019:2607194 Authors: Hawamdeh H, Al-Zoubi B, Al Sharqi Y, Qasrawi A, Abdel-Aziz Y, Barbar M Abstract [This corrects the article DOI: 10.1155/2016/6718590.]. PMID: 31097958 [PubMed - in process]
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
ConclusionsThis study demonstrates that the risk of developing a second IMID is significantly higher for individuals who have already experienced a first IMID in a large and contemporary US claims database. Certain pairs of IMIDs co-occur more frequently than others. The risk of developing subsequent IMIDs may be an important consideration for clinicians when selecting treatment strategies.FundingAbbvie.
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 15 May 2019Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Maja Šikic Pogacar, Veljko Vlaisavljević, Eva Turk, Dušanka Mičetić-TurkAbstractObjectiveCeliac disease is associated with higher risk of infertility, recurrent abortions, and adverse outcomes in pregnancy and in puerperium. The aim of the study was to analyse the association between celiac disease and reproductive disorders in the group of celiac patients and compare these to healthy controls.MethodsA retrospective case-control matched study. The association between celia...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
In the United States and other developed countries, we have seen a shift over the past several decades in the types of illness people struggle with. Public health campaigns around vaccination, sanitation, and judicious use of antibiotics have largely eradicated many infectious illnesses. As the nature of disease has shifted to inflammatory conditions, we’ve seen a striking increase in allergy and autoimmune conditions such as diabetes, obesity, inflammatory bowel disease, celiac disease, and multiple sclerosis. The microbiome — the varied and teeming colonies of gut bacteria inside of us — may be helping ...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Digestive Disorders Family Planning and Pregnancy Inflammation Probiotics Source Type: blogs
Abstract Background and objectives: Dermatitis herpetiformis (DH) is a blistering dermatosis, which shares common immunologic features with celiac disease (CD). The aim of the present study was to explore the performance of a panel of CD-related antibodies and IL-17A in Bulgarian patients with DH. Materials and Methods: Serum samples from 26 DH patients at mean age 53 ± 15 years and 20 healthy controls were assessed for anti-tissue transglutaminase (anti-tTG), anti-deamidated gliadin peptides (anti-DGP), anti-actin antibodies (AAA), and IL-17A by enzyme linked immuno-sorbent assay (ELISA), as well as anti-t...
Source: Medicina (Kaunas) - Category: Universities & Medical Training Authors: Tags: Medicina (Kaunas) Source Type: research
Celiac disease is associated with higher risk of infertility, recurrent abortions, and adverse outcomes in pregnancy and in puerperium. The aim of the study was to analyse the association between celiac disease and reproductive disorders in the group of celiac patients and compare these to healthy controls.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Full length article Source Type: research
Little is known about the immunopathogenic relationship between celiac disease and systemic autoimmune diseases, such as primary Sjögren’s syndrome and systemic sclerosis. But new research indicates that screening for celiac disease may benefit patients newly diagnosed with systemic autoimmune diseases, as well as supports the idea that celiac disease may accelerate the development of systemic autoimmune disease...
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Conditions Systemic Inflammatory Syndromes celiac disease primary Sjogren's syndrome (pSS) screening Systemic sclerosis Source Type: research
If you can ’t eat it I won’teat it, he says to my sisterwhen she tests positivefor celiac. Then they makeof themselves a small countryin North Jersey where wheatwill not grow, nor be bought,nor be baked into breador cake, and in their solidaritythey will no longer miss it.Already her spine has a commaat it s base where the boneis brittling like candy: symptomof the thing she has. Let otherssavor what is soft and warmfrom an oven, torn into.They will step from the garden—arms full of yellow heirlooms,deep greens to be sautéedfor supper, rice. Two glassesof wine before the washing up.
Source: JAMA - Category: General Medicine Source Type: research
DNA and Cell Biology, Ahead of Print.
Source: DNA and Cell Biology - Category: Cytology Authors: Source Type: research
AbstractFor decades, the pathogenesis of a variety of human diseases has been attributed to increased intestinal paracellular permeability even though scientific evidence supporting this hypothesis has been tenuous. Nevertheless, during the past decade, there have been a growing number of publications focused on human genetics, the gut microbiome, and proteomics, suggesting that loss of mucosal barrier function, particularly in the gastrointestinal tract, may substantially affect antigen trafficking, ultimately causing chronic inflammation, including autoimmunity, in genetically predisposed individuals. The gut mucosa work...
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
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