Propofol sedation for flexible bronchoscopy (fb) and endobronchial ultrasound bronchoscopy (ebus): our experience.

We aimed to study the safety of propofol deep sedation managed by interventional pulmonologist in our centreObservational retrospective study of 900FB/EBUS between 2014-16. We collected epidemiological variables, indications, monitoring parameters and diagnostic procedures(DP)Sedation complications: oxygen saturation(SO2)<90% or fall≥6%, systolic blood pressure(SBP)>160mmHg, SBP<90mmHg, heart rate(HR)>120bpm or HR<60bpmStatistical analysis SPSSv22900 procedures analyzed (75%ambulatory, 78%male, average age65±12years). Indications in order were: neoplasms(36%) and mediastinal staging(15%), followed by infections(10%) and hemoptysis(8%)Almost 2000DP were performed including bronchial aspirate(700), brushing(231), bronchoalveolar lavage(81), transbronchial needle aspiration(182), endobronchial and transbronchial biopsy(371) and EBUS(212). The majority of patients underwent 1(32%) or 2(22%)DPPropofol average dose was 276mg(3.9mg/kg), classifying patients into 4groups: <2mg/kg(21%) 2-4mg/kg(38%) 4-6mg/kg(23%) and >6mg/kg(15%)SO2<90% occurred in 15% patients and falls>6%: 15%; SBP>160mmHg: 22%; SBP<90mmHg: 10%; HR>120bpm: 3% and HR<60bpm 22%About complications arising from DP: moderate bleeding happened in 3%, 2 patients suffered stomach expansion and only 1 required intubation and transfer to ICUNo relation was found between complications rate and propofol dose(p=0.4); while hypotension was significantly higher in patients receiving...

Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Andres Porras, A. M., Jaurrieta Largo, S., Lobato Astiarraga, I., De Vega Sanchez, B., Garcia Onieva, A. I., Chourio Estaba, M. J., Alaejos Pascua, M. I., Carton Sanchez, M. B., Ramos Cancelo, I., Disdier Vicente, C. Tags: Interventional Pulmonology Source Type: research