Upregulation of intestinal mucosal mast cells expressing VPAC1 in close proximity to vasoactive intestinal polypeptide in inflammatory bowel disease and murine colitis

Conclusions and InferencesCommunication between MCs and VIP is upregulated during IBD and mice colitis. In CD patients, the epithelium next to FAE seems to be more involved than the surrounding VE, suggesting increased MC ‐VIP‐interactions in this intestinal region.

Source: Neurogastroenterology and Motility - November 8, 2018 Category: Gastroenterology Authors: Maite Casado ‐Bedmar, Stéphanie D. S. Heil, Pär Myrelid, Johan D. Söderholm, Åsa V. Keita Tags: ORIGINAL ARTICLE Source Type: research