HIV-1 second-line failure and drug resistance at high-level and low-level viremia in Western Kenya

Conclusion: High resistance upon second-line failure exists at levels above and below guideline-recommended virologic-failure threshold, impacting future treatment options. Optimization of care should include increased viral load monitoring, resistance testing and third-line ART access, and consideration of lowering the virologic failure threshold, though this demands further investigation.
Source: AIDS - Category: Infectious Diseases Tags: CLINICAL SCIENCE Source Type: research