Methacycline displays a strong efficacy in reducing toxicity in a SCA3 Caenorhabditis elegans model
ConclusionsThe apparent absence of toxic effects displayed by methacycline, along with its stronger efficacy in contrasting expanded ataxin-3 toxicity, makes it a possible candidate for a chronic treatment of the disease.
Source: Biochimica et Biophysica Acta (BBA) General Subjects - Category: Biochemistry Source Type: research
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