Combined Effect of IL-12R β2 and IL-23R Expression on Prognosis of Patients with Laryngeal Cancer

Conclusion: IL-12R β2 and IL-23R create a homeostasis within the tumor cells and TILs, and this homeostasis affects prognosis. While the intrinsic mechanisms of epigenetic immunoediting for IL-12Rβ2 and IL-23R remain unknown, additional larger and functional studies are warranted for validation.Cell Physiol Biochem 2018;50:1041 –1054
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research