FoxO4 promotes myocardial ischemia-reperfusion injury: the role of oxidative stress-induced apoptosis.

In conclusion, the FoxO4/ROS pathway represents a potentially novel mechanism underlying apoptosis during myocardial I/R injury. Therapeutic strategies targeting FoxO4 might represent new treatments for myocardial I/R injury. PMID: 30323875 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/30323875?dopt=Abstract

Source: American Journal of Translational Research - October 17, 2018 Category: Research Tags: Am J Transl Res Source Type: research