Preclinical Evaluation of Ropivacaine in 2 Liposomal Modified Systems.

CONCLUSIONS: All new liposomal formulations containing 0.75% RVC were able to change the pharmacokinetics and enhance anesthesia duration due to slow release of RVC from liposomes without inducing significant toxic effects to local tissues.
PMID: 30303863 [PubMed - as supplied by publisher]

Source: Anesthesia and Analgesia - October 9, 2018 Category: Anesthesiology Authors: Rennó CC, Papini JZB, Cereda CMS, Martinez E, Montalli VA, de Paula E, Pedrazzoli Júnior J, Calafatti SA, Tofoli GR Tags: Anesth Analg Source Type: research