A novel simple diagnostic algorithm for rapid and accurate detection of anemia etiology in patients with advanced heart failure

Anemia is common in heart failure (HF) and is associated with increased mortality and morbidity. (1,2) We have previously shown that iron deficiency (ID) is the cause of anemia in 73% of patients with advanced HF. (3) Importantly, ID has emerged as a therapeutic target in HF. (4-7) However, ID detection in HF is problematic: traditional cut-off values of ferritin have low diagnostic value in HF, (8) and bone marrow (BM) aspiration, the diagnostic gold standard, is invasive. In the FAIR-HF and CONFIRM-HF trials ID was defined as ferritin

Source: Journal of Cardiac Failure - October 8, 2018 Category: Cardiology Authors: Elisabeth Kaldara, Konstantinos Malliaras, Despina Barbarousi, Chris J. Kapelios, Stella Vakrou, Ioannis Tachliabouris, John N. Nanas Source Type: research