Vitamin D deficiency in outpatients with inflammatory bowel disease: prevalence and association with clinical-biological activity.
Vitamin D deficiency in outpatients with inflammatory bowel disease: prevalence and association with clinical-biological activity. Rev Esp Enferm Dig. 2018 Oct 04;111: Authors: Olmedo Martín RV, González Molero I, Olveira Fuster G, Amo Trillo V, Jiménez Pérez M Abstract INTRODUCTION: there are few data on the prevalence of vitamin D deficiency in patients with inflammatory bowel disease (IBD) in Spain. A deficiency could be associated with a worse course of the disease. AIM: to determine the prevalence of 25-hydroxyvitamin D (25OHD) deficiency in a cohort of outpatients with IBD and assess its association with clinical and biological activity, quality of life and psychological symptoms. METHODS: a cross-sectional, single-center observational study was performed. The study variables were obtained via clinical interviews, medical chart review and validated questionnaires (Hospital Anxiety and Depression Scale and Short Quality of Life in Inflammatory Bowel Disease Questionnaire). 25OHD was measured in the same laboratory by an electro-chemiluminescence immunoassay. RESULTS: the study included 224 patients. The prevalence of vitamin D deficiency in Crohn's disease and ulcerative colitis was 33.3% and 20.3%, respectively. In Crohn's disease, vitamin D deficiency was associated with a higher clinical activity (p
Publication date: Available online 28 March 2020Source: Mental Health and Physical ActivityAuthor(s): Kristen M. Lucibello, Emily M. Paolucci, Jeffrey D. Graham, Jennifer J. Heisz
In this study, we aimed to evaluate the correlation between LCI observation and clinical relapse rate in UC patients. We retrospectively analyzed UC patients who underwent total colonoscopy between August 2016 and October 2018 at our facility with Mayo endoscopic scores of 0 or 1. We assessed the correlation between orange-like color lesion (defined as LCI-scarlet color lesions) and clinical relapse rate (requiring additional treatment for UC) during the 1-year follow-up period. Fifty-eight patients (22 female, 36 male; median age at diagnosis, 47.2 (18-80) years) who underwent colonoscopy were analyzed. During the 1-year ...
In this study, we used qPCR to quantify mtDNA copy number in 15 Holocaust survivors and 102 of their second- and third-generation descendants from the Czech Republic, many of whom suffer from PTSD, and compared them to controls in the respective generations. We found no significant difference in mtDNA copy number in the Holocaust survivors compared to controls, whether they have PTSD or not, and no significant elevation in descendants of female Holocaust survivors as compared to descendants of male survivors or controls. Our results showed no evidence of persistence or inheritance of mtDNA changes in Holocaust survivors, t...
Publication date: Available online 28 March 2020Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): N.K. Schaal, P. Hepp, M. Heil, O.T. Wolf, C. Hagenbeck, M. Fleisch, T. Fehm
A hospital ship heads to New York, and more than 17 states now tally over 1,000 cases. Deaths have surged in Italy and Spain, and Russia is closing all its borders, including maritime boundaries.
Publication date: Available online 27 March 2020Source: Brain, Behavior, and ImmunityAuthor(s): Richard T. Liu, Aislinn D. Rowan-Nash, Ana E. Sheehan, Rachel F.L. Walsh, Christina M. Sanzari, Benjamin J. Korry, Peter Belenky
Publication date: Available online 27 March 2020Source: Brain StimulationAuthor(s): Maxim Zavorotnyy, Rebecca Zoellner, Henning Rekate, Patricia Dietsche, Miriam Bopp, Jens Sommer, Tina Meller, Axel Krug, Igor Nenadić
Publication date: Available online 27 March 2020Source: The LancetAuthor(s): Oriol Mitjà, Àlex Arenas, Xavier Rodó, Aurelio Tobias, Joe Brew, José M Benlloch, on behalf of 62 signatories
Rate of fatalities suggests Britain on similar trajectory to Italy and Spain, Europe’s worst-hit countries