Positive effects of α-asarone on transplanted neural progenitor cells in a murine model of ischemic stroke
Conclusionα-asarone may promote NPC proliferation and differentiation into neuron-lineage cells by activating β-catenin, cyclin D1, and ERK. Moreover, α-asarone treatment facilitated neurofunctional recovery after NPC transplantation in a murine model of ischemic stroke. Therefore, α-asarone is a potential adjunct treatment to NPC therapy for functional restoration after brain injuries such as ischemic stroke.Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
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