Epidemiology of familial hypercholesterolaemia: Community and clinical

Familial hypercholesterolaemia (FH) is a genetic disorder affecting the metabolism of low-density lipoprotein (LDL) particles, leading to high LDL-cholesterol levels maintained over time and higher risk of cardiovascular disease (CVD) early in life.Contemporary studies have challenged prior estimations of FH prevalence and suggest this condition to be more frequent than previously considered, with an overall prevalence rate of 1:200 –300 individuals in the general population (1:160,000–300,000 for homozygous FH).
Source: Atherosclerosis - Category: Cardiology Authors: Tags: Review article Source Type: research