Functional proteasome complex is required for turnover of islet amyloid polypeptide in pancreatic {beta}-cells [Cell Biology]
This study suggests a novel regulatory pathway in β-cells involving proteasome, FOXA2, and IAPP, which can be possibly targeted to regulate hIAPP levels and islet amyloidosis in T2DM.
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Diti Chatterjee Bhowmick, Aleksandar Jeremic Tags: Protein Synthesis and Degradation Source Type: research
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