Age-Related Change in 5-HT6 Receptor Availability in Healthy Male Volunteers Measured with 11C-GSK215083 PET

Conclusion: To our knowledge, this was the first in vivo study on humans to examine the effect of age on 5-HT6 receptor availability. The study demonstrated a significant age-related decline in 5-HT6 availability (BPND) in the caudate and putamen.

Source: Journal of Nuclear Medicine - September 4, 2018 Category: Nuclear Medicine Authors: Radhakrishnan, R., Nabulsi, N., Gaiser, E., Gallezot, J.-D., Henry, S., Planeta, B., Lin, S.-f., Ropchan, J., Williams, W., Morris, E., DSouza, D. C., Huang, Y., Carson, R. E., Matuskey, D. Tags: Clinical Source Type: research