NGF and BDNF expression in mouse DRG after spared nerve injury

We examined nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) expression in the DRGs of SNI model mice. NGF and BDNF levels increased in the injured L3 DRG, while NGF decreased in the intact L5 DRG. These data offer a new point of view on the role of these neurotrophins in neuropathic pain induced by peripheral nerve injury.Graphical abstract
Source: Neuroscience Letters - Category: Neuroscience Source Type: research