Initial Riociguat Monotherapy and Transition from Sildenafil to Riociguat in Patients with Idiopathic Pulmonary Arterial Hypertension: Influence on Right Heart Remodeling and Right Ventricular –Pulmonary Arterial Coupling

ConclusionThese results support the proven efficacy of riociguat in patients with IPAH, including treatment-na ïve patients and those switching to riociguat following failure to achieve treatment goals with sildenafil, and suggest that it may be possible to delay disease progression in this patient group.
Source: Lung - Category: Respiratory Medicine Source Type: research